This course is so inconsistent I don't even know how to write a short review on it. Content-wise, from the videos, there is nothing too difficult and most of the topics taught are fairly easy to follow. The same goes for the quizzes where most of the content is from the lectures, or simple analyses to be performed on provided datasets on the Galaxy web platform.
Cut to the course project and it is a completely different story. The execution of the project is extremely poor, there is insufficient background information provided in the lectures and the course project instructions themselves are vague. I understand the nature of genomic data science which involves a lot of collaboration and searching on the web for the appropriate tools (as pointed out by the instructor on the forums, who also encouraged free discussion on the forums wrt the project), but some level of background and/or forum support by staff needs to be provided.
On the bright side I have never seen such a collaborative group of students on a MOOC, when anyone had an issue almost immediately someone would jump in and clarify a concept or try to explain how to do a task (well, we had to since the staff weren't very helpful). The evaluations were nearly as difficult as doing the course project to start with, and I get the vibe that most people were just giving everyone full marks just because they did not know how to or it was just too time consuming to perform a proper evaluation which is a pity as peer evaluation is a wonderful opportunity to learn.
The other major problem faced was a topic covered in the videos which was aimed at more advanced students where the instructor demonstrated how to set up a local instance of Galaxy supported by Amazon Web Services. I watched the video but did not attempt to do so myself, but because terminating the instance was not covered in the lectures many people who did try out what the instructor was demonstrating found themselves being charged hefty sums by Amazon because of the continued use of cloud services (I think the highest charge I saw was over 700 dollars). Naturally students weren't too happy about that!
Galaxy is a tremendously useful platform but this course probably isn't the way to go to learn how to use it. There are many tutorials on Galaxy itself which are probably as informative as doing this course.