Coursera: Introductory Organic Chemistry - Part 1

 with  Jeffrey S. Moore
This course surveys structural chemistry of organic compounds with an emphasis on electronic structure, conformation and stereochemistry. Concepts and models are developed to build intuition about the stability and reactivity of organic compounds. These concepts will prepare students for a mechanistic-based approach to learning organic reactivity. Emphasis will also be placed on developing problem-solving skills unique to organic chemistry. This course (Introductory Organic Chemistry Part I) together with Introductory Organic Chemistry Part II are equivalent to a first-semester organic chemistry course; these courses and the subsequent courses (Intermediate Organic Chemistry Parts I and II) are especially suited for students in agricultural, nutritional and biological sciences, as well as pre-medical, pre-dental, and pre-veterinary programs.


Module Key Concepts Week 1: The Building Blocks of Organic Chemistry
  • Period 2 Elements
  • Formal Charge
  • Stability Trends
  • Bonding Patterns
  • Functional Groups
Week 2: The Language of Organic Chemistry
  • Basic Organic Nomenclature
  • Molecular Symmetry
  • Chirality
  • Stereochemical Descriptors
  • Representations of 3-Dimensional Structures
Week 3: Electrons in Molecules
  • Resonance
  • Wave Properties of Electrons
  • Atomic Orbitals
  • Linear Combination of Atomic Orbitals
Week 4: Molecular Orbital Theory
  • Constructing Simple MO Diagrams
  • Inferring Reactivity From MO Diagrams
  • The Hybrid Orbital Approximation
  • Frontier Orbital Theory
Week 5: Molecules in Motion
  • Conformations of Linear Molecules
  • Stability of Cyclic Molecules
  • Conformations of Cyclohexanes
  • Coordinate Diagrams
Week 6: Understanding Reactivity
  • Bond Energy Changes
  • Transition States
  • Nucleophiles and Electrophiles
  • Acid-Base Equilibria
Week 7: Organic Reactions, Part I
  • Substitution Reactions
  • Elimination Reactions
  • Discriminating Related Reaction Mechanisms
Week 8: Organic Reactions, Part II
  • Stereospecificity of Substitution and Elimination Reaction Mechanisms
  • Carbocation Rearrangements
  • Activated C-O Electrophiles
  • Carbon-Based Nucleophiles
7 Student
Cost Free Online Course (Audit)
Pace Finished
Subject Chemistry
Provider Coursera
Language English
Certificates Certificate Available
Hours 8-10 hours a week
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FAQ View All
What are MOOCs?
MOOCs stand for Massive Open Online Courses. These are free online courses from universities around the world (eg. Stanford Harvard MIT) offered to anyone with an internet connection.
How do I register?
To register for a course, click on "Go to Class" button on the course page. This will take you to the providers website where you can register for the course.
How do these MOOCs or free online courses work?
MOOCs are designed for an online audience, teaching primarily through short (5-20 min.) pre recorded video lectures, that you watch on weekly schedule when convenient for you.  They also have student discussion forums, homework/assignments, and online quizzes or exams.

Reviews for Coursera's Introductory Organic Chemistry - Part 1
3.1 Based on 7 reviews

  • 5 star 14%
  • 4 stars 29%
  • 3 stars 29%
  • 2 star 14%
  • 1 star 14%

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  • 1
3.0 2 years ago
by Auggie Huber audited this course.
Whenever I click on the "go to class" button an Error 404 Message appears on the page? Any help for this kind of problem? Thanks
Was this review helpful to you? Yes
1.0 4 months ago
by Hemang Parekh dropped this course and found the course difficulty to be very hard.
Link to GoTo Class does not work. I found a reference on and decided to take the course, wasted more than 3 hours trying for find out if this works from anywhere. There are no free online video lectures available for the course, it probably did at some point but then they have been deliberately dropped (seems so).

Regardless, is is a waste of time.

Prof. Moore, You may have the best teaching abilities and best material but if you do not make it available you are just wasting everyone's time.
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3.0 3 years ago
Michael Or is taking this course right now, spending 7 hours a week on it and found the course difficulty to be medium.
3 people found
this review helpful
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4.0 3 years ago
by Sudhir is taking this course right now.
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5.0 4 years ago
Miguel Chamosa is taking this course right now.
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2.0 2 years ago
Michael Nome completed this course.
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4.0 2 years ago
by Marquerite is taking this course right now.
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