subject
Intro

Coursera: Genomic and Precision Medicine

 with  Jeanette McCarthy and Robert Nussbaum
Precision medicine has the potential to change fundamentally how health care is practiced, but requires a health care workforce that understands the complexities of this field. One important component of Precision Medicine is the use of an individual’s genomic information to offer targeted treatment, tailored to the individual. Our course aims to provide participants with some baseline knowledge of genomics, an overview of the clinical applications of genomic medicine, the skills to evaluate the clinical validity and utility of new tests, and an appreciation of the associated ethical and social issues inherent in this field.

The course is geared toward practicing health care providers, although it should be accessible to anyone with a background in the biological sciences and a basic understanding of genetics. It is designed to be succinct and clinically-focused, offering both conceptual and practical information about real-world applications of genomics. Two lessons offer a basic primer on molecular genomics relevant to the individual patient as well as to patient populations. The remaining five lessons focus on five applications of genomics and present the material as case studies, highlighting the strengths, limitations, and issues that arise in the use of each test.

Syllabus

Week 1
This week you will learn foundational concepts about the structure and function of the human genome and different types of genetic and non-genetic variation that occur.

Week 2
This week, Drs. Nussbaum and Norton will describe the use of genomics in the reproductive setting: carrier testing, non-invasive prenatal screening, prenatal diagnosis of Mendelian diseases, and newborn screening.

Week 3
This week Dr. Nussbaum will review the use of next-generation sequencing for solving diagnostic dilemmas.

Week 4
This week we will explore the genetics of common, complex diseases and the population genetics methods used to uncover genetic associations.

Week 5
This week Dr. Mendelsohn joins me to roll play some scenarios to teach you about predictive tests for common, complex diseases and direct-to-consumer testing.

Week 6
This week we discuss pharmacogenomic testing for drug selection, dosing and predicting adverse effects of commonly prescribed drugs.

Week 7
Our final lecture explores tumor profiling for targeting cancer treatment and the use of blood-based gene expression profiles in cancer prognosis.

2 Student
reviews
Cost Free Online Course (Audit)
Pace Upcoming
Subject Health Care
Provider Coursera
Language English
Certificates Paid Certificate Available
Hours 1-3 hours a week
Calendar 7 weeks long
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What are MOOCs?
MOOCs stand for Massive Open Online Courses. These are free online courses from universities around the world (eg. Stanford Harvard MIT) offered to anyone with an internet connection.
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To register for a course, click on "Go to Class" button on the course page. This will take you to the providers website where you can register for the course.
How do these MOOCs or free online courses work?
MOOCs are designed for an online audience, teaching primarily through short (5-20 min.) pre recorded video lectures, that you watch on weekly schedule when convenient for you.  They also have student discussion forums, homework/assignments, and online quizzes or exams.

2 reviews for Coursera's Genomic and Precision Medicine

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2 months ago
Antoine Ciolkovitch completed this course, spending 2 hours a week on it and found the course difficulty to be easy.
Very informative. A clear overview and useful guidelines . The course offered by Pr Jeanette McCarthy is well structured and the self-pace/switch session system makes the work easy to organize .
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2 years ago
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James Warren completed this course.
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