Background: I have worked at a startup for the past 3 years, so I was already familiar with some concepts.
Content: the content is not difficult. In general, they are teaching you things that you must do to be successful at a startup, but nothing they teach will guarantee success. That's the difficulty of entrepreneurship. The key value of this and many other courses is to give you a framework of reference to use to brainstorm and evaluate new venture opportunities. It is very valuable to be able to draw from the professors' experiences when doing this.
Omar F. completed this course, spending 1 hours a week on it and found the course difficulty to be very easy.