This course covers the learning outcomes and goals of understanding clinical research in cancer genomics, how it impacts cancer treatment, and the new paradigm in cancer treatment through targeted therapy and genomic profiling. The course teaches skills such as tumor profiling, identifying actionable mutations, and interpreting genomic testing reports. The teaching method includes lectures, case studies, and discussions. The intended audience for this course includes healthcare professionals, researchers, and individuals interested in cancer genomics and precision medicine.
Overview
Syllabus
Intro
Stanford Cancer Institute
Personalized Medicine
Opportunities to Increase Cancer Survival
Precision Medicine in Cancer. Tumor Profiling and Therapeutics
New Paradigm in Cancer Treatment: Targeted Therapy
Cancer Genomic Profiling and Treatment: A New Paradigm
Genomic Profiling: What to Expect
"Actionable" mutations
Stanford Molecular Tumor Board Workflow
Genomic testing for patients: example report
Challenges: Cancer Genomic Medicine
Tumor Heterogeneity
Exceptional Responses
Key Concept: DRIVER mutations
Basket Trials
Umbrella Protocol 4 basket studies - early results
NCI-MATCH Schema
Clinical Outcomes: Intermountain Cohort Study
Cancer Genomics Tumor Board Case
Patient Case: Colon Cancer
Partial Response to AKT-inhibitor on genomic basket trial
Other general resources for your cancer information search
Taught by
Stanford Health Care
Tags
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